But Goldwire, limited to six points in the first half because of foul trouble, scored Charlotte's last 11 points, including a pair of 3-pointers that tied the game at 55 and 58.
Goldwire drew an off-the-ball foul on Luis Guzman to lead to his game-winning free throws.
Tied at 8 at the 15:01 mark of the first half, Charlotte went on a 21-5 run during the next nine minutes and led 29-13 with just under 6 minutes to play. The 49ers shot 9-for-16 from the floor during the run, while the Owls missed nine of 11 shots.
The lead got to 33-16 before Temple closed the first half with eight straight points.
Lamont Mack tied a career high with 18 points for Charlotte. Mark Tyndale had 17 points and Dionte Christmas had 13 for Temple.
