Officials say they will trim 250 positions - nearly 4 percent of the 6,400 member work force - by the end of April.
Hospital president and CEO Scott Wolfe says the cuts will come from management and staff positions in nearly all departments but there will be no elimination or curtailment of services or programs.
Officials say the cuts will come by not filling vacant positions, offering employees early retirement incentives, and by layoffs, if needed.
Wolfe says the staff reduction plan is expected to result in savings of $10 million to $15 million.
Reading Hospital is Berks County's largest employer.
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