The four are charged with murder, attempted murder, unlawful weapon possession and other charges in the death of Tamrah Leonard, 13.
Authorities say the group sprayed automatic gunfire at a block party near Martin Luther King and Rossell Avenue while trying to retaliate for a gang shooting at a Trenton night club the night before.
"It was strictly retaliation, that's all. One minute of stupidity ended with a 13-year-old girl being killed, senselessly," said Police Director Irving Bradley.
The Warren brothers and the 17-year-old were arrested overnight.
Police say Robert Humphrey was already in custody on drug charges.
More arrests in this case are expected.
Leonard was killed on Sunday, June 7th.
It happened as residents gathered for a campaign block party for the youth minister of the New Black Panther party.
Somebody in a passing vehicle sprayed the area with bullets, hitting Leonard.
She was walking about six blocks from one aunt's house to another aunt's home to meet her mother, when she detoured through Martin Luther King Boulevard.
It was about 6:30, and a block party sponsored by city council hopeful Divine Allah was in full swing, when two cars pulled up and gunfire erupted.
Allah says gang members were invited to that block party and says the event, which attracted about 100 people, was billed as an event to help stop the violence in Trenton's North Ward.
Allah, who plans to run for the city council in 2010, says he believes Tamrah Leonard's killing was an act of senseless violence.
Tamrah Leonard was a 7th grader at Monument Elementary School. She was a a dancer, cheerleader and honor roll student.
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