RELATED SLIDESHOW: Pictures of the bank robbers
Police say one suspect threw a teller on the ground as another suspect held a gun to another employee, demanding the key to the vault.
However, police say the teller was unable to do what was asked, so the men fled the bank in an unknown direction.
In surveillance pictures released by police, one suspect could be seen brandishing two handguns, and the bandits are wearing white masks with eye-holes cut out.
No one was injured during the incident.
Anyone with information regarding the crime is being asked to contact police at 302-322-9800.
You can get the latest crime statistics from the Philadelphia Police by CLICKING HERE for the force's crime data mapping site.