Vaughn's spokesman, Alan Nierob, said Monday the 39-year-old "Couples Retreat" and "Swingers" actor wed 31-year-old real estate agent Kyla Weber in a small private ceremony Saturday outside Chicago.
He said the nuptials were attended by family and close friends.
It is the first marriage for both Weber and "The Break-Up" and "Four Christmases" leading man.
Vaughn previously dated "Break-Up" co-star Jennifer Aniston.