It happened around 10:36 a.m. at the branch at 100 East Swedesford Road.
At around 10:36 a.m., the suspect entered the bank and demanded money. The teller handed him the cash, and the man fled the bank.
Police say he took off in a white or light-colored minivan driven by a white woman with long, shaggy brown hair.
The suspect is described as a white male in his mid 20's, approximately 5'7" to 5'10" tall, thin build, with short-cropped blonde hair, unshaven with a mustache and goatee.
He was wearing a dark blue New York Yankees baseball cap, a baggy thermal long-sleeve t-shirt, and cargo-style pants.
His hands and/or clothes may be stained, the FBI said.
Anyone with information is asked to call the FBI at 215-418-4000 or the Tredyffrin Township Police Department.