The state Agriculture Department says aerial spraying will cover a 99-acre tract in Mullica in Atlantic County.
Last year, the state sprayed almost 36,000 acres in 15 counties.
Previous spraying has taken a toll on the caterpillars. Gypsy moths also are falling victim to predatory parasites and a fungus.
State Agriculture Secretary Douglas Fisher says monitoring will continue because the damaging moths were found in scattered pockets elsewhere in the state.
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Information from: Courier-Post