It happened along the 2600 block of West Arizona Street shortly after 9:30 p.m.
A man, believed to be in his late 20s to mid 30s, was shot multiple times and found unresponsive on the street.
He was rushed to Temple University Hospital in an unknown condition.
The man had been shot in the back, neck and head.
Police are looking for multiple suspects who got into a car and sped off.