39-year-old Manuel Albandoz was arrested and charged with involuntary manslaughter.
The crash happened around 12:30 a.m. Sunday.
A 41-year-old woman was riding her bike near the intersection of Torresdale and Adams avenues when she was hit by a black Ford Taurus, leaving her critically injured.
She was rushed to the hospital where she was pronounced dead.
Police say they have identified the woman, but are not releasing her name until her family can be notified.
The car was found near the scene after the crash. Police say the car did not belong to Albandoz.