The incident took place in two different intersections in Northern Liberties.
At around 6:00 p.m., at 7th and Brown streets, police found a 56-year-old man lying dead on the street. He had been stabbed in the stomach.
Around the corner, at 8th Street and Fairmount Avenue, a 31-year-old man was discovered stabbed in the neck.
He was rushed by medics to Hahnemann Hospital for treatment.
At this time, the suspect remains at large.
There is no word on a motive for the attacks.