Firefighters responded to the 600 block of North 21st Street early Saturday morning.
When they arrived, they encountered flames shooting from the third floor of a rowhome. The porch of the home was also on fire.
Two men broke bones when they jumped out of the burning home. A woman in the home escaped unhurt.
The fire spread to two adjoining homes before firefighters could contain it.
Ten people were left homeless by the fire, no word yet on what sparked it.
