Bucks County authorities said 58-year-old Domingo Negron turned himself in Wednesday in the death of 54-year-old Joseph Kwiatkowski.
Kwiatkowski was living in Florida when he died. A medical examiner there said his death was caused by the bullet that paralyzed him during a 1973 brawl in Warminster.
Negron served time for assault and firearms charges in the case. Defense attorney Craig Penglase said Negron will fight the charges.
A grand jury recommended murder charges Tuesday after a 14-month investigation.
The case is similar to the 1966 shooting of Philadelphia police Officer William Barclay that was prosecuted as a murder after he died in 2007. William Barnes was acquitted but remains behind bars on parole violations.