The shooting occurred shortly after 10:30 p.m. on the 2200 block of Market Street in front of Brandywine Community United Methodist Church.
Wilmington police say a man, believed to be in his 30's, suffered gunshot wounds to his abdominal area.
He was rushed by medics to the hospital in extremely critical condition.
Police are looking into the possibility that robbery may have been a motive.
At this time, there's no known connection between the victim and the fact that the incident occurred in front of a church.
Police are searching for a suspect.