The shooting took place along the 4700 block of Vista Street shortly after 8:30 p.m.
Police say a 29-year-old woman was shot multiple times.
Police believe the gunfire originated outside the rear of the home.
Police and medics responded and transported the woman to Aria Health's Torresdale Campus.
Police say it is not clear if the woman was the intended target as there were others in the home at the time.
No arrests have been made.