The crash, involving a motorcycle and an SUV, happened around 8:20 p.m. along the 2000 block of Black Horse Pike.
Police say Paul Callahan, 24, of Sewell, was riding a motorcycle at a high rate of speed on the Black Horse Pike approaching Georgia Avenue.
Meanwhile, a GMC Jimmy driven by 20-year-old David Polisano, Jr. of Williamstown, was at the stop sign on Georgia Avenue. As the GMC pulled into the intersection, it was hit by the motorcycle.
Both Callahan and Polisano were killed.
The passenger in the GMC, 39-year-old Robin Engwiller of Williamstown, was last reported in critical but stable condition at Cooper University Hospital.