The series of accidents occurred around 9:10 p.m. Sunday at the intersection of 28th Street and Girard Avenue in the Brewerytown section of Philadelphia.
The driver struck a police cruiser, as well as two other vehicles.
Police say the accident was caused by a woman driving the wrong direction and running a red light.
Three people, including two police officers, were transported to area hospitals, all with non-life-threatening injuries.
Police are continuing to investigate.