In a statement Tuesday, the actress said she is leaving the medical series after seven years as Dr. Lisa Cuddy.
The decision followed much consideration and brings mixed feelings, Edelstein said: She's disappointed at leaving a character she loved playing but is excited about the opportunities in acting and producing that are ahead.
Edelstein didn't offer details on her plans.
"House" stars /*Hugh Laurie*/ in the title role of a cranky but brilliant doctor. He and Edelstein's Cuddy, a hospital administrator, had explored a relationship this season.
"House" will return this fall at 9 p.m. EDT Monday, Fox announced this week.
