It happened along the 800 block of Sanger Street shortly before 9:00 p.m.
Police and medics were called to a report of a stabbing.
Authorities say a 33-year-old woman was stabbed four times, once in the head, once in the face and twice in the left arm.
A 54-year-old male who attempted to break up the melee suffered a knife wound to his right arm. He is the landlord of the building.
Both victims were transported to Albert Einstein Medical Center.
Police arrested a 50-year old man who was wielding a knife.
No further information about the incident has been released.