Philadelphia's Roy Halladay took home two awards of his own. The Phillies ace won as the best MLB player and for best moment for his playoff no-hitter against the Cincinnati Reds.
Meanwhile, DeSean Jackon and LeSean McCoy accepted on behalf of the Philadelphia Eagles for Best Game in their "Miracle at the New Meadowlands" against the New York Giants.
Dirk Nowitzki picked up a pair of trophies, including male athlete of the year, and his Dallas Mavericks were chosen as the best team Wednesday night at the ESPY Awards.
Nowitzki also won as best NBA player during ESPN's live telecast from the Nokia Theatre. Rick Carlisle was named best coach for leading the Mavericks to the NBA championship.
Nowitzki, who was the MVP of the NBA finals, is the first NBA player to be named top male athlete since Michael Jordan in 1993. Also nominated for the award were Packers quarterback Aaron Rodgers, five-time NASCAR champion Jimmie Johnson and tennis star Rafael Nadal, who each won awards in other categories.
Olympic gold medalist Lindsey Vonn won female athlete of the year for the second year in a row. She is the first female to win the honor consecutive times since Annika Sorenstam in 2005-06. Vonn won in a group that included Maya Moore, Lauren Jackson and Kelly Clark.
Saturday Night Live comedian Seth Myers hosted the show for a second straight year. He opened the telecast by joking about the NFL and NBA lockouts before taking some digs at the Miami Heat. He then cracked some jokes about Brian Wilson's unique outfit choice.
The always eccentric Wilson would have won the award for best dressed athlete, had there been one. All eyes were on the San Francisco Giants closer as he walked down the red carpet in a full-body spandex tuxedo, complete with black high-tops and a cane.
Fresh off leading the Bruins to their first Stanley Cup crown in 39 years, Boston goaltender Tim Thomas won for best championship performance and best NHL player.