Paul Millsap added 14 points and 14 rebounds for the Jazz, who have beaten the 76ers seven straight times at home and in 21 of the last 23 meetings in Salt Lake City.
Favors started at center for Utah in place of Al Jefferson, who did not play because of an inflamed right ankle.
Jrue Holiday scored a season-high 22 points for the Sixers and reserve Lou Williams added 20 but missed what would have been a game-tying 3-pointer at the buzzer.
TheJazz trailed by as many as 13 points in the second quarter before rallying.
