The fire was reported around 9:30 a.m. along the 2200 block of West Huntingdon Street.
Upon their arrival, crews reported heavy fire showing and quickly brought the flames under control.
One resident, who had jumped from a second story window, was transported to the hospital with a fractured ankle.
Animal control was called in to assist two injured dogs found in the basement. Three other dogs were found deceased in the yard.
The cause of the fire is under investigation.