Producers said Monday that the former "Taxi" star will play a Vegas wiseguy in the show, which makes its debut in November in Toronto. It is then headed to Broadway in the spring of 2013.
The musical features music and lyrics by Tony Award winner Jason Robert Brown and a book by Andrew Bergman, who also directed and wrote the film.
The 1992 movie starred James Caan, Nicolas Cage and Sarah Jessica Parker. It tells the story of a reluctant groom whose bride-to-be is courted by Danza's character.
Danza was on Broadway in Mel Brooks' musical "The Producers" and in the 1997 production of "A View from the Bridge."
