The crash happened at the intersection of Hurffville Crosskeys Road and Theresa Road in Washington Township.
The view from Chopper 6 HD showed significant damage to both the SUV and the school bus.
Rescuers on the scene say the driver of the SUV suffered multiple injuries. There was no immediate word on the condition of the bus driver.
There were no children on the school bus at the time of the crash.
An investigation into how this crash happened continues.