The crash happened around 2:50 p.m. in the southbound lanes about one mile south of Martin Lurther King Boulevard.
Police say 19-year-old Jamia Y. Jackson, of Wilmington, failed to stop for slowed traffic and struck the rear of another car.
That caused a chain-reaction crash that involved another five vehicles.
Two people suffered minor injuries in this crash.
Two right-hand lanes of I-95 SB were closed for about 40 minutes as the crash was investigated and cleared.
Police say charges are expected as a result of this crash.
