The two-alarm fire broke out around 4:30 a.m. along the 600 block of Point Street.
The flames quickly spread to the adjoining homes on both sides.
One man was found dead and a woman suffered burns all over her body. She was taken to Temple University Hospital in critical condition.
Authorities say the man's body was found inside one of the three homes destroyed.
They released pictures of the religious necklace the victim was wearing in hopes of identifying him.
It is the Infant of Prague, Our Lady of Mount Carmel medal.
Anyone with information that may help police identify the deceased victim is asked to contact Investigator Rich Nicolella of the Camden County Prosecutor's Office at 856-225-8436 or Camden County Police Detective Randy Smith at 856-757-7420.