Their 15th district van flipped over and hit a telephone pole after colliding with a Toyota Camry.
The crash happened at Harbison and Cheltenham Avenues, just before 9:00 a.m..
Police say the van had its lights and sirens on when it was broadsided by the Camry.
The officers are hospitalized with back and neck pain.
A woman and an infant in the car were not injured.
Investigators have not said who caused the wreck.