Rod Barajas, brought in by the Pirates in the offseason to provide some power, doubled off Philadelphia reliever Joe Blanton (0-1) leading off the inning and pinch-runner McKenry came home three batters later when Presley beat out an infield single.
Juan Cruz (1-0), a non-roster invitee to spring training, won in relief. Presley had two of Pittsburgh's six hits.
Shane Victorino and Placido Polanco had two hits apiece for Philadelphia. The Phillies got two baserunners in both the ninth and 10th innings but couldn't break through.
Cliff Lee gave up one run in six innings for Philadelphia.
