Spokesman Paul Shefrin said Clark had a heart attack Wednesday morning at Saint John's hospital in Santa Monica, where he had gone the day before for an outpatient procedure.
Clark suffered a stroke in 2004 that affected his ability to speak and walk.
The man long dubbed "the world's oldest teenager" because of his boyish appearance had strong ties to the Philadelphia area.
After graduating from Syracuse University, Clark got a job at WFIL, what is now 6abc, in 1952.
His first show in Philadelphia was called "Dick Clark's Caravan of Music."
Clark joined "Bandstand" in 1956 after Bob Horn, who'd been the host since its 1952 debut, was fired. Under Clark's guidance, it went from a local Philadelphia show taped at WFIL studios to a national phenomenon.
The original "American Bandstand" was one of network TV's longest-running series as part of ABC's daytime lineup from 1957 to 1987. It later aired for a year in syndication and briefly on the USA Network. Over the years, it introduced stars ranging from Buddy Holly to Madonna. The show's status as an American cultural institution was solidified when Clark donated Bandstand's original podium and backdrop to the Smithsonian Institution.
"I played records, the kids danced, and America watched," was how Clark once described the series' simplicity. In his 1958 hit "Sweet Little Sixteen," Chuck Berry sang that "they'll be rocking on Bandstand, Philadelphia, P-A."
6abc President & General Manager Bernie Prazenica issued the following statement on the passing of Dick Clark: "Dick Clark was one of the great pioneers at WFIL-TV (now WPVI-TV). He will always be a part of our family and our legacy, and we offer our deepest condolences to his family."
As a host, Clark had the smooth delivery of a seasoned radio announcer. As a producer, he had an ear for a hit record. He also knew how to make wary adults welcome this odd new breed of music in their homes.
"I went to the studio a couple of times to dance. It was fun. [Dick Clark] was like a young kid, somebody that never aged," Francis Spivey of Mt. Airy said.
Clark endured accusations that he was in with the squares, with critic Lester Bangs defining Bandstand as "a leggily acceptable euphemism of the teenage experience." In a 1985 interview, Clark acknowledged the complaints. "But I knew at the time that if we didn't make the presentation to the older generation palatable, it could kill it."
"So along with Little Richard and Chuck Berry and the Platters and the Crows and the Jayhawks ... the boys wore coats and ties and the girls combed their hair and they all looked like sweet little kids into a high school dance," he said.
Clark met Chubby Checker, then a 19-year-old Ernest Evans, in Philadelphia and gave him the start on American Bandstand that propelled him in the industry.
"The greatest event in the music industry happened on his show. Chubby Checker did the twist on American Bandstand and the world change," Checker said.
Chubby Checker last saw Clark late last year in California and they spent hours remembering the good times.
"If Elvis was the king of rock and roll than Dick Clark is the king of all the disc jockeys and he died today. We will miss him, but we all are indebted to him because he did something that we all enjoy," Checker told Action News at his Paoli home.
Clark defended pop artists and artistic freedom, the Rock and Roll Hall of Fame said in an online biography of the 1993 inductee. He helped give black artists their due by playing original R&B recordings instead of cover versions by white performers, and he condemned censorship.
At age 14, Tommy Mc Carthy, now the music director of WOGL radio, was a dancer on Bandstand.
Dick Clark became his mentor who encouraged him as he began his own DJ career. The two stayed in touch, even after Clark suffered his stroke seven years ago.
McCarthy says the loss to the world of music is a huge one.
"It's a personal loss, but to the music industry - he discovered more talent than anybody in this planet. "American Bandstand" was the MTV of the '50s and '60s.," McCarthy said.
Bob Clayton of Wilmington was only 16 years old when he and Justine Carrelli were picked by Dick Clark to be among his profiled dancers on Bandstand. That was 1957.
"He affected my life in a way at the time I would have never thought, because you're 16 years old," Clayton said.
Other dancers on Bandstand remember Clark as a real gentleman.
"The way he was spoke to the people while he was on the set was the way he spoke to people when it was off set," Maxine Ostroff of South Philadelphia said.
"I remember his laugh. He had a wonderful laugh and a wonderful smile," Sharon Shecter-Cohen of East Norriton, Pa. said.
President Barack Obama noted the nostalgia. "More important than his groundbreaking achievements was the way he made us feel - as young and vibrant and optimistic as he was," Obama said in a statement.
Clark bridged the rebellious new music scene and traditional show business, and equally comfortable whether chatting about music with Sam Cooke or bantering with Ed McMahon about TV bloopers. He thrived as the founder of Dick Clark Productions, supplying movies, game and music shows, beauty contests and more to TV. Among his credits: "The $25,000 Pyramid," ''TV's Bloopers and Practical Jokes" and the American Music Awards.
"I grew up watching him on TV and he never grew old. It's a loss to the entertainment world," Pat Julian of East Falls said.
Dick Clark and show business pioneer Kal Rudman were disc jockeys on the Philadelphia airwaves in the late 50s and 60s.
Rudman believes the death of the legend resonates with so many who grew up during that time because Clark formed, shaped, and molded their childhoods.
"If he played a brand new record once or twice, the records poured out of the record store, that is power," Rudman said.
For a time in the 1980s, he had shows on all three networks and was listed among the Forbes 400 of wealthiest Americans. Clark also was part of radio as partner in the United Stations Radio Network, which provided programs - including Clark's - to thousands of stations.
"There's hardly any segment of the population that doesn't see what I do," Clark told The Associated Press in a 1985 interview. "It can be embarrassing. People come up to me and say, 'I love your show,' and I have no idea which one they're talking about."
Broadcasting pioneer Lew Klein and executive producer of American Bandstand says no one will ever compare to Dick Clark.
"When I think of people who had an impact, not only with the music and the entertainment, but in the style of conducting yourself as a celebrity, I certainly put Dick at the top of the list as a gentleman," Klein said.
His stroke in December 2004 forced him to miss his annual appearance on "Dick Clark's New Year's Rockin' Eve." He returned the following year and, although his speech at times was difficult to understand, many praised his bravery, including other stroke victims.
Ryan Seacrest, who took over main hosting duties on the countdown show from Clark, said in a statement Wednesday that he was "deeply saddened."
"I idolized him from the start, and I was graced early on in my career with his generous advice and counsel," Seacrest said. "He was a remarkable host and businessman and left a rich legacy to television audiences around the world. We will all miss him."
"I'm just thankful I'm still able to enjoy this once-a-year treat," Clark told The Associated Press by e-mail in December 2008 as another New Year's Eve approached.
Clark was honored at the Emmy Awards in 2006, telling the crowd: "I have accomplished my childhood dream, to be in show business. Everybody should be so lucky to have their dreams come true. I've been truly blessed."
He was born Richard Wagstaff Clark in Mount Vernon, N.Y., in 1929. His father, Richard Augustus Clark, was a sales manager who worked in radio.
Clark idolized his athletic older brother, Bradley, who was killed in World War II. In his 1976 autobiography, "Rock, Roll & Remember," Clark recalled how radio helped ease his loneliness and turned him into a fan of Steve Allen, Arthur Godfrey and other popular hosts.
From Godfrey, he said, he learned that "a radio announcer does not talk to 'those of you out there in radio land'; a radio announcer talks to me as an individual."
Clark began his career in the mailroom of a Utica, N.Y., radio station in 1945. By age 26, he was a broadcasting veteran, with nine years' experience on radio and TV stations in Syracuse and Utica, N.Y., and Philadelphia. He held a bachelor's degree from Syracuse University.
While in Philadelphia, Clark befriended McMahon, who later credited Clark for introducing him to his future "Tonight Show" boss, Johnny Carson.
In the 1960s, "American Bandstand" moved from black-and-white to color, from weekday broadcasts to once-a-week Saturday shows and from Philadelphia to Los Angeles. Although its influence started to ebb, it still featured some of the biggest stars of each decade, whether Janis Joplin, the Jackson 5, Talking Heads or Prince. But Clark never did book two of rock's iconic groups, the Beatles and the Rolling Stones. Elvis Presley also never performed, although Clark managed an on-air telephone interview while Presley was in the Army.
Philadelphia radio legend Jerry Blavat was a friend of Clark's going back to the 1950s.
"He was my friend, he wrote the introduction to my book 'You Only Rock Once.' It's sad for me because there will never be a Dick Clark, there will never be someone in this industry to help young people with careers to be exposed. This guy did more for our music than anyone else ever," Blavat told Action News at the Sugarhouse Casino.
When Michael Jackson died in June 2009, Clark recalled working with him since he was a child, adding, "of all the thousands of entertainers I have worked with, Michael was THE most outstanding. Many have tried and will try to copy him, but his talent will never be matched."
Clark kept more than records spinning with his Dick Clark Productions. Its credits included the Academy of Country Music and Golden Globe awards; TV movies including the Emmy-winning "The Woman Who Willed a Miracle" (1984), the "$25,000 Pyramid" game show and the 1985 film "Remo Williams: The Adventure Begins." Clark himself made a cameo on "The Fresh Prince of Bel-Air" and a dramatic appearance as a witness on the original "Perry Mason." He was an involuntary part of Michael Moore's Academy Award-winning "Bowling for Columbine," in which Clark is seen brushing off Moore as the filmmaker confronts him about working conditions at a restaurant owned by Clark.
In 1974, at ABC's request, Clark created the American Music Awards after the network lost the broadcast rights to the Grammy Awards.
He was also an author, with "Dick Clark's American Bandstand" and such self-help books as "Dick Clark's Program for Success in Your Business and Personal Life" and "Looking Great, Staying Young." His unchanging looks inspired a joke in "Peggy Sue Gets Married," the 1986 comedy starring Kathleen Turner as an unhappy wife and mother transported back to 1960. Watching Clark on a black and white TV set, she shakes her head in amazement, "Look at that man, he never ages."
Clark's clean-cut image survived a music industry scandal. In 1960, during a congressional investigation of "payola" or bribery in the record and radio industry, Clark was called on to testify.
He was cleared of any suspicions but was required by ABC to divest himself of record-company interests to avoid any appearance of a conflict of interest. The demand cost him $8 million, Clark once estimated. His holdings included partial ownership of Swan Records, which later released the first U.S. version of the Beatles' smash "She Loves You."
In 2004, Clark announced plans for a revamped version of "American Bandstand." The show, produced with "American Idol" creator Simon Fuller, was to feature a host other than Clark.
He was diagnosed with Type 2 diabetes in 1994 and served as spokesman for the American Association of Diabetes Educators.
Clark, twice divorced, had a son, Richard Augustus II, with first wife Barbara Mallery and two children, Duane and Cindy, with second wife Loretta Martin. He married Kari Wigton in 1977.
One local fan summed up the feelings of many: "The man is irreplaceable. He's an icon in Philadelphia, in fact, nationally. There will never be another Dick Clark."
Lynn Elber of The Associated Press contributed to this article.