Investigators say a gunman opened fire at 1:35 a.m. inside a home on the 800 block of North Madison Street in Wilmington.
Police and medics responded and found 24-year-old Monique Boyce in the basement shot to death; she had her 10-day-old baby in her arms.
Police say an intruder gained entry through the rear of the house.
The gunman shot Boyce's 25-year-old boyfriend who jumped from a second floor window and flagged down an officer a few blocks away.
When they returned, they found Boyce.
Her baby was treated on the scene by paramedics. Her 4-year-old daughter was also in the house and was unharmed.
The children are now staying with family members.
"She's a great mother; she always loved her kids. If you go on her Facebook page, she praises her kids. She was just so happy to be with them," friend Shakira Romeo said.
Police believe Boyce's 25-year-old boyfriend was the target.He has an extensive criminal record.
They believe there may be a connection to another murder nearby just 20 minutes earlier.
It was around 1:15 a.m. when police were called to the intersection of 9th and Grant after a car crashed on the lawn of the Woodlawn Library.
26-year-old William Pennewell was found shot behind the wheel of his car. He pronounced dead soon after at the hospital.
He also has an extensive record and was recently released on bail.
Police are also investigating a shooting at 10th and Pine yesterday afternoon.
16-year-old Anthony Newman was shot and killed.
He had just recently been released from juvenile detention.
Police say this is all the result of a violent drug culture.
"We're looking at a common theme of extensive criminal histories with violent acts, drug involvement, being on prohibition, being currently released from a correctional system," Wilmington Police Chief Michael Szczerba said.
Boyce was the only one involved in this wave of violence without a criminal record.
She worked as a manager at a nearby fast food restaurant.
"She was very responsible because she was working. She could have been doing all kind of illegal things, but she was working on an honest job," neighbor Valerie Mitchell said.
So far, police have no suspects in any of the three murders, but sources say they have collected 'useful evidence' from the house on Madison Street.
Anyone with information is asked to call 911 or contact Detective Division at 302-576-3620.