It happened at 1:50 p.m. on July 23rd at Carmen's Grocery Store at 952 E. Woodlawn Street.
Surveillance video released by police showed the four men enter the store.
Police say two of the men were armed with handguns.
Once inside, the suspects entered the office, took an undetermined amount of cash, then fled south on Devon Street.
Police described the suspects as:
Suspect #1: Black male, 16-18 years-of-age, 6'0", thin build, light blue hooded sweatshirt, black pants with white stripes, silver handgun.
Suspect #2: Black male, 16-18 years-of-age, 5'9", thin build ,red baseball cap with black trim and possibly with "Miami" on the front, gray sweatshirt, dark pants, armed with a handgun.
Suspect #3: Black male, gray hooded sweatshirt, dark pants, brown work boots.
Suspect #4: Black male, gray hooded sweatshirt, dark jeans, black sneakers.
Anyone with information is asked to contact Philadelphia Police at 215-686-TIPS (8477) or through phillypolice.com.