Four people were wounded by gunfire along the 900 block of East Price Street.
Police say at least 20 people were in the area around 11:45 p.m. when the shooting occurred.
Numerous cars were shot up along with several homes. The occupants inside the homes were not injured.
Officials found 14 gun casing at the scene, and have determined that three semi automatic weapons were used.
All of the victims were men in their 20s. Two of the men are listed in critical condition and the other two are stable.
So far, there is no description of the drive-by vehicle as police continue to investigate.