The crash occurred just before 2:00 a.m. at the intersection of 6th and Girard Avenue.
Police say a 32-year-old woman driving an SUV collided with the rear end of a SEPTA trolley, knocking it off its tracks.
According to officials, two men in the SUV fled the scene leaving the woman trapped in the SUV.
The woman had to be extricated from the vehicle and was taken to the hospital and is listed in stable condition.
The trolley operator was not seriously hurt and there were no passengers onboard.
There is no word on whether the police have caught the men who left the scene of the accident.