The crash happened at 7:35 a.m. Friday on the White Horse Pike near United States Avenue.
The accident happened in Clementon but the bus came to rest in Lindenwold.
The female driver of the van suffered serious injuries and was taken to Cooper Hospital in stable condition.
A passenger in the van suffered minor injuries.
No students were onboard at the time of the crash and the bus driver was not seriously injured..
The view from Chopper 6 HD shows the van with heavy front-end damage up against a utility pole.
The school bus was stopped at the scene, also with front-end damage.
No word what caused the crash. An investigation in ongoing.