Sandra Lee, 52, of the 700 block of North 37th Street died in the crash on the Spring Garden Street Bridge, just off the I-76 ramp.
She was the passenger in a Nissan being driven by her husband, 56-year-old Alonzo Lee.
"I'm very disturbed. Very," said Lee's cousin, Dennis Hunter. "She went to work every day, came home every day. Never bothered nobody, never had any problems."
Police say the couple was driving on the eastbound ramp off I-76 when the driver of another car struck their vehicle.
The Nissan went up on a curb and flipped onto its side.
Police say the driver of the striking vehicle, a 30-year-old man, fled on foot but was later stopped and arrested at 35th and Lancaster.
The suspect has not been named by police. However, investigators say he faces a number of charges including Homicide by Vehicle and DUI.