The Nets have lost their last two preseason games on their $1 billion home court after opening it with a win over Washington on Monday night.
The 76ers led by as much as 12 points in the third quarter but Brooklyn cut it to 97-96 with 3:07 left in the game after a pair of free throws by Brook Lopez, who led the Nets with 23 points and nine rebounds.
But Thaddeus Young answered with a fadeaway jumper to make it 99-96 and Wright followed with two free throws to extend Philadelphia's lead to 101-96 with 2:06 remaining. Nick Young's 3-pointer made it 104-96 and Deron Williams, who had 22 points, missed a 3-pointer.
The Nets have one more preseason game remaining, Wednesday night at the Nassau Coliseum against the New York Knicks, before the teams open against each other on Nov. 1.
Philadelphia has won its last three games and has two remaining, at Boston on Sunday night and then Monday night at home against the Knicks.