It happened around 7:00 Wednesday evening along Middletown Boulevard, which encompasses the Oxford Valley Mall.
Authorities say an SUV collided with another vehicle. The impact of the crash sent the second car onto its roof.
Fire officials responded to the scene and had to extricate one person from the wreckage.
Two victims were taken to St. Mary's Hospital for treatment. Their injuries were said to be non-life threatening.
No word what sparked the accident.