It happened around 2:00 Saturday morning in the northbound outer lanes of the road near 5th Street.
Authorities say the driver of a Pontiac Bonneville was speeding when he lost control and slammed into the tree.
The impact of the crash ejected the driver and his passenger from the vehicle.
Both victims were taken to Albert Einstein Hospital.
The passenger was pronounced dead and the driver is listed in stable condition with a broken arm.
No charges have been filed. The crash remains under investigation.