The incident happened just after 6:00 p.m. on the 12000 block of Knights Road, near Academy Road.
Police say a 74-year-old woman was hit by a vehicle as she tried to cross the street near Franklin Mills Mall.
The vehicle stopped at the scene.
The victim was taken to Aria Hospital Torresdale Division where she died a short time later.
There is no word yet on the identity of the victim or if charges will be filed.