The shooting happened around 1:00 a.m. outside Eddie's Cafe in the 6500 block of Dicks Avenue.
Police say a confrontation between two women led to a fight between the men who were with them, which spilled out into the street.
The men brought out handguns and began firing, police say. A 35-year-old man was hit four times and rushed to the Hospital of the University of Pennsylvania.
So far, there have been no arrests in this case.