Jamal Crawford also scored 20 points and Matt Barnes had 11 for the Pacific Division-leading Clippers. Eric Bledsoe scored 10 points while DeAndre Jordan grabbed 10 rebounds.
The Clippers closed out their season-high eight-game road trip at 4-4, including consecutive wins at New York and Philadelphia.
Los Angeles won the finale with ease without guard Chauncey Billups and forward Caron Butler. Both players were nursing sore lower backs and were replaced in the starting lineup by Matt Barnes and Willie Green.
Nick Young led the Sixers with 29 points while Jrue Holiday, Evan Turner and Jeremy Pargo had 10 each. Spencer Hawes had 10 rebounds.