Reyes led off the game with a single and the Dominican Republic team never let up, roughing up Hamels for 12 hits and eight runs in 2 2-3 innings, his third start of spring training.
Reyes, Robinson Cano and Ramirez each homered. Ramirez and Miguel Tejada had four hits apiece for the Dominican team. Cano had three hits and three RBIs and Edwin Encarnacion also had three hits.
Dominican right-hander Samuel Deduno allowed one run on three hits. Deduno struck out three and didn't walk a batter.
Laynce Nix hit his first home run of the spring for the Phillies.