It happened around 7:30 p.m. Wednesday in the 100 block of Indian Mills Road in Shamong Township.
Police say the driver somehow lost control of the vehicle and crashed.
The impact ejected the driver as the vehicle burst into flames.
The driver, identified as 22-year-old Kyle Stevenson, was taken to Virtua Marlton Hospital with life threatening injuries.
Police say Stevenson was the only one in the vehicle.