It happened before 12:30 p.m. on northbound 202 near Route 29 in East Whiteland Township.
Police say a tractor trailer hit the Jersey barrier separating the northbound and southbound lanes.
The impact damaged the truck and caused 2 of the concrete barriers to fall into one of the southbound lanes.
Both northbound lanes were blocked as a tow truck moved in to haul away the big rig.
One northbound lane and one southbound lane remained blocked after that, as crews worked to clear the damaged Jersey barriers.
One person sustained minor injuries and taken to an area hospital for treatment.
There was no immediate word what caused the truck driver to lose control, or if any charges would be filed.