The exact total number of people being laid off was not immediately available.
Multiple sources inside the district tell Action News that Superintendent William Hite has sent out emails to a number of school personnel outlining the layoffs.
News of the job losses comes as the district continues trying to close a $304 million deficit.
Phone calls to the district, the teacher's union and the administration were not returned Friday morning.
Last week, the School Reform Commission approved a $2.4 billion spending plan that includes deep cuts in art, music, athletics and other programs.
Opponents called it the "Doomsday Budget."
The district was required to pass a budget by last Friday. Officials say some of the cuts can be rescinded if they receive extra funding this summer; they've asked the city and state to kick in $180 million and for unions to agree to about $130 million in concessions.
Stay with Action News and 6abc.com as this story develops.