Police say the vehicle slammed into two trees on the 700 block of Schlosser Road in Harleysville just before 4:00 a.m.
The impact of the collision caused the car to overturn.
The driver was pronounced dead at the scene.
The cause for the accident remains under investigation.
Anyone who may have witnessed the crash is urged to contact the Lower Salford Township Police Department at 215-256-9500.