The crash happened around 11:20 a.m. at the intersection of Route 1 and Valley Road.
Police say a BMW and a crane truck collided in the intersection.
The 58,000 lb. truck left the roadway and hit the Wawa Corporate University sign.
A man who was doing work on that sign was also hit.
The BMW involved caught fire following the crash.
The man working on the sign and the BMW driver were both taken to the hospital with non-life-threatening injuries.
An investigation into this crash continues.