Officers were called to the Five Star Supermarket at 60th and Springfield Avenue around 5:30 a.m. Saturday.
According to investigators, thousands of dollars worth of cigarettes and an undetermined amount of cash were taken.
Police say it appears the burglar or burglars got in through the roof.
Anyone with information is asked to contact Philadelphia Police at 215-686-TIPS (8477), text a tip to PPD TIP (773847) or through PhillyPolice.com.
