The robbery happened at 8:35 p.m. Friday inside of the Lacquer Lounge Nail Salon, located at 501 Fitzwater Street.
According to police, the suspect entered the salon armed with a large knife and began demanding jewelry from the customers and employees.
After getting jewelry from those inside the suspect fled on foot east on Fitzwater Street.
The suspect is described as a white male with possible acne or acne scarring on face, standing 5'10" to 6'1" with a thin build. He was last seen wearing a black or dark grey hooded sweatshirt, baseball cap, and armed with a black military or Kbar style knife.
Anyone with information is asked to contact Philadelphia Police at 215-686-TIPS (8477), text a tip to PPD TIP (773847) or through PhillyPolice.com.