The incident happened just before 10:00 a.m. inside the Keystone Industrial Port Complex, located on Ben Fairless Drive in Morrisville.
The two victims were transported by paramedics to area hospitals. One patient went to Capital Health and another went to Helen Fuld Medical Center.
The condition of the two patients is still unknown, however injuries are not considered life threatening.
The nature of the hazmat is not yet clear.
Initial reports indicated that the incident happened at the Kinder Morgan Energy Company, located nearby, but that information proved to be incorrect.