Kelly McKeown, 34, has been missing since Thursday, December 19th.
Police say she was last seen in the 2200 block of South 3rd Street.
McKeown is 5'9" tall, 175 pounds with short blonde hair and hazel eyes.
She was last seen wearing a black t-shirt, blue jeans and a light tan windbreaker.
Police say she suffers from depression.
Anyone with information is asked to call South Detective Division at 215-686-3013.